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Vibrational Circular Dichroism Spectrometer

Jasco VCD Jasco VCD 2

Vibrational Circular Dichroism Spectrometer: an essential tool for absolute configuration of molecules

FVS-6000

JASCO has developed the FVS-6000 high performance VCD (Vibrational Circular Dichroism) spectrometer with the most advanced DSP electronics and auto-alignment mechanism. The FVS-6000 not only allows you to easily obtain fingerprint VCD spectra, but also has several unique features such as a measurement range extension option of 4000 ~ 750 cm-1. Since the CD signals in the infrared region are one or more orders of magnitude lower than ECD signals in the UV-Vis region, high sensitivity and stability are required for a VCD spectrometer. The FVS-6000 is the VCD spectrometer of choice for highly sensitive VCD measurements.

Optimized optics. The FVS-6000 employs a 28° interferometer to reduce polarization effects and reflective optics to eliminate artifacts caused by birefringence for high-quality VCD data. Additionally a newly developed beam splitter provides unparallel sensitivity in the spectral region of interest

Thermal stability. The isolated mount of the IR light source and the thermal control of the PEM crystal offers long-term baseline stability.

VCD auto alignment. The auto alignment function optimizes the VCD optics to reduce linear anisotropy artifacts. No manual alignment is required when the detector and/or optical filters are exchanged.

Lock-in detection by DSP. Phase-sensitive lock-in detection by DSP (Digital Signal Processing) with a sophisticated algorithm optimized for VCD offers drastic improvement of the S/N ratio.

Purge capability. The optics, sample chamber and detector housing are all purgeable to obtain high-precision data free of environmental interference.

Wide band coverage. The FVS-6000 can provide spectra over a wide spectral range (4000 ~ 750 cm-1), enabling the measurement of OH and NH bands. Detectors can easily be exchanged with no manual alignment, and optical filters can be switched by a PC-controlled 6-position filter wheel.

Narrow band mode. The narrow band mode allows measurements of small peaks at targeted absorption bands with high sensitivity by using optional band filters.

Variety of sample cells. A thermostatted cell holder, 3-position sample shuttle, and range of small-volume liquid cells are available as options.

Spectra ManagerTM II.  Spectra Manager II software, the cross-platform control and analysis package for all JASCO spectrometers, offers quick and easy VCD data acquisition and analysis. Theoretically calculated VCD intensities from a commercially available calculation software can be plotted as simulated spectra to be compared with the experimental data for further tertiary structure analysis of molecules.

VFT-4000 Vibrational Circular Dichroism (VCD) attachment

The VFT-4000 is a VCD attachment for the FT/IR-4000/6000 FT-IR spectrometers, developed for measuring vibrational circular dichroism in the infrared region. The VFT-4000 can be used to obtain very useful information for the optical activity of carbohydrates and provide tertiary structure identification of chiral molecules. Since the CD signals in the infrared region are one or more orders of magnitude lower than ECD signals in the UV-Vis region, the VCD spectrometer needs high sensitivity and high stability. The VFT-4000 enables highly stable and sensitive measurement using lock-in detection by a DSP (digital signal processor) with a sophisticated algorithm optimized for VCD as well as thermal control of the PEM.
The VFT-4000 can be easily integrated with an installed FT/IR-4000/6000 in the field, providing a single system for the structural analysis of various optical active substances
Wide band coverage. The VFT-4000 can cover a wide spectral range (4000 ~ 750 cm-1), enabling the measurement of OH and NH bands. Detectors can be easily exchanged with no manual alignment, and optical filters can be switched by a PC-controlled 6-position filter wheel.
VCD auto alignment. An auto-alignment function optimizes the VCD optics to reduce linear anisotropy artifacts. No manual alignment is required when a detector and/or optical filters are exchanged.
Narrow band mode. The narrow band mode allows measurements of small peaks at targeted absorption bands with high sensitivity by using optional band filters.
Purge capability. The optics, sample chamber and detector housing are all purgeable to obtain high precision data free of environmental interference.

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Kontakt: Mikael Alfredsson på Göteborgskontoret, 0709-119309
             Mats Grapne Askfelt på Stockholms-kontoret, 0709-119301
De kan även nås via epost. Skriv förnamn.efternamn@kovalent.se.
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