The Game Changer in Microwave Digestion
The ultraWAVE fully endorses our vision in microwave sample preparation: it has already revolutionized and enhanced the way analytical chemists think to sample preparation for trace metal analysis in hundreds of laboratories all over the world.
The ultraWAVE is based on the SRC (Single Reaction Chamber technology), invented by Milestone several years ago (Patents pending). SRC technology achieves extraordinary performance capabilities combining microwave heating with a high-pressure reactor which acts simultaneously as microwave cavity and vessel. The ultraWAVE chamber is sealed, pressurized, heated, cooled, vented, and opened via a dedicated touch-screen control terminal. Loading a rack of samples into the chamber is the only manual operation in an otherwise fully automated process of microwave-assisted sample preparation. The outer surfaces of the vessel remain at room temperature throughout the entire microwave heating cycle. As a result, the ultraWAVE is dramatically less labor intensive and easier to use compared to conventional microwave digestion systems.
● High performance: The highest temperatures & pressure capabilities and the fastest cooling time
● Increased throughput: Double throughput of traditional microwave acid digestion instruments.
● No batching required: Simultaneous digestion of any sample type combination.
● Ease of use: Cleaning of digestion vials is not necessary. No vessel assembly/disassembly.
● Expertise and Support: 30-years experience at your lab with the Milestone Connect.
● Compliance: USP 232/233 Chapters, ICH Q3D Guidelines and FDA regulation 21 CFR part 11.
At the core of the ultraWAVE is a TFM-lined reaction vessel. Samples are weighed into vials, and suitable reagents are added. Rack with vials is automatically lowered into the reaction chamber.
2. Closing and pressurizing
The chamber is sealed and pressurized with inert gas, which physically acts as a cap for the vials, avoiding boiling of the solutions and preventing cross contamination.
2. Heating and cooling
Microwave energy is applied, with all samples at the same temperature and pressure conditions. At the end of the microwave run, a cooling device rapidly lowers the temperature of the solutions.
4. Pressure release and opening
The entire rack is automatically lifted up to facilitate the removal of the solution vials. As a visual aid for the user, the color of the backlit logo indicates the process status.
The ultraWAVE rack configurations include 4, 5, 8, 15, 19, 22 and 26 position and combinations thereof. Vials are available in TFM, quartz or disposable glass, and are fitted with loose TFM caps to ensure pressure equalization. Unlike conventional microwave digestion systems, no vessel assembly or disassembly is required. The use of disposable glass vials eliminates the cleaning step, further enhancing the lab’s workflow. The fast assembly of the vials, the automatic closing and opening cut the handling time, reducing the labour cost up to 50%.
Like all Milestone products, the ultraWAVE has been designed with operator safety of paramount importance: it has been developed for being used with any acid or combination thereof, and every single reactor is tested at a pressure up to 330 bar. A thick acrylic shield surrounds the working area, and runs cannot be started unless the chamber clamps are in correct position. Temperature and pressure are monitored 20 times/sec, automatically adjusting microwave power to control even highly exothermic reactions.
One method for all samples
Any combination of sample types (food, environmental, polymer, cosmetic, pharmaceutical, geological, chemical, and petrochemical) can be digested simultaneously; no need to batch samples into identical types. No method development is needed, as the same method can be used for nearly any sample. And for the first time, blanks and reference standards of any matrix can be digested alongside samples, enabling true in-run digestion quality control.
R=Standard Reference. B=Analytical Blank.
The UltraWAVE is capable of processing in a single run different unknown samples along with certified reference materials and analytical blanks.
Superior digestion quality
Operating up to 199 bar pressure and 300°C temperature, the ultraWAVE enables the complete digestion of extremely difficult samples and of large amounts of organics, outperforming any other microwave digestion system. Unlike conventional microwave digestion systems, every sample is under direct temperature and pressure control, so there is no need to rely on a reference vessel or to an indirect control such as infrared temperature sensors.
The ultraWAVE reaches high temperatures faster, cools faster (10 minutes from 200°C to room temperature), and is capable of higher pressure and temperature than any other system. The ultraWAVE does not suffer of any cross contamination among samples. Blanks are significantly lower than with conventional microwaves, since less acid is used and vials have a much less surface in contact with the analytical solution.
Compared to any other conventional microwave digestion systems, the ultraWAVE is significantly easier to use, thus dramatically improving the laboratory work flow. Up to 26 samples are processed in 45 minutes start to finish. Ease to say that the ultraWAVE sample throughput is far better than any other microwave systems.
All samples are processed in a single run at the same temperature and pressure, eliminating the need to run multiple digestion cycles for different samples or matrices. The use of disposable glass vials eliminates the cleaning step, further enhancing the ultraWAVE productivity.
Low Operation Cost
The ultraWAVE accommodates inexpensive disposable vials.
Opening and closing the vessels, assembly and disassembly of the rotors are not required in the ultraWAVE anymore. The handling of the system is dramatically reduced, and tedious and time-consuming procedures are eliminated.
The technology used in all conventional microwave lead to create stressful conditions in the TFM vessels, substantially reducing their lifetime. The design of SRC technology in the ultraWAVE strongly contributes to the reduction of the running costs by using inexpensive and handy vials suitable for any metals and trace metals determination.
Smart sofware designed around you
The ultraWAVE is controlled via a compact external terminal with an easy-to-read, bright, full-color, touchscreen display. Multiple USB and Ethernet ports are provided, for interfacing the instrument to external devices and to the local laboratory network. The terminal runs the Milestone easyWAVE, a completely new user-friendly, icon-driven, and multi-language software. Just recall a previously stored method or create a new one; press the Start icon and the system will automatically follow the user defined temperature profile using a sophisticated PID algorithm.
Hundreds of applications, including all US EPA methods, are preloaded, eliminating any need for method development.
Need to fulfill regulatory requirements?
The Milestone Validation Packages include several protocols in order to fulfill regulatory requirements, such as the Good Manufacturing Practice (GMP) guidelines that, along with our superior support and expertise, will be by your side throughout the whole process. Our experts will support you with the right confi guration, with a dedicated procedure for your samples, with a demonstration of the system’s capabilities and with a complete validation package that includes: DQ (Design Qualification), IQ (Installation Qualification), OQ (Operational Qualification), PQ (Performance Qualification) and the requalification. All the tests carried out by our service engineers are guaranteed by certified test equipment, providing high accuracy and meeting all the regulatory requirements. Our software is fully compliant with the FDA regulation 21 CFR part 11, with an exhaustive audit trail for complete traceability. The MVP is one of the multiple services offered by Milestone to ensure the highest industry standards in customer support.