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Jasco LC-MS

Jasco LC-MS

Easy to use
LC-MS-systems for HPLC to preparative LC

The LC-4000-MS mass spectrometry system has been developed to harness the power of a single quadrapole MS with an easy to use HPLC system.

Single Quad LC-MS

The CMS expression is a high resolution mass spectrometer with wide mass range and a choice of sources including ESI, APCI and ASAP – a direct injection method.The CMS expression is a high resolution mass spectrometer with wide mass range and a choice of sources including ESI, APCI and ASAP – a direct injection method.The separation system can be configured for a wide range of applications, including standard HPLC or UHPLC, to take full advantage of the speed and sensitivity of the mass spectrometer.

  • ● 300 mm wide footprint
  • ● Each system component is completely stackable into a modest height
  • ● The system is fully integrated with complete system monitoring
  • ● All user replaceable components are accessible through the front panel
  • ● Vertical leak/drain system to channel away solvent
  • ● Integrated earthquake securing option
  • ● Compact MS ESI and APCI

Product Specialist

Mats Grapne Kovalent

Mats Grapne

"More than 30 years experience in the field of HPLC, Spectroscopy and other analytical equipments. Contact me if you have questions or need a quotation"

mats.grapne@kovalent.se

08-473 33 40

  • Unlimited pump options

    The LC-4000 Series includes various pump options for solvent delivery with accurate and pulseless flow, with flexible configuration for isocratic or binary and quaternary gradients.

  • Flexible autosampler

    The AS-4150 autosampler has capacity for up to 180 – 2 mL samples and includes full or variable loop injections. The sample pre-load feature eliminates sample loading time between injections for the fastest sample cycle time to get results faster.

  • Column ovens from analytical to preparative

    Several optional column ovens offer the advantage of temperature control with single column or multi-columns for rapid method development.

  • Compact MS or advanced versions

    The mass spectrometer can be a simple, cost effective CMS expression single quadrapole instrument, or a higher specification tandem MS with either a triple quadrapole (TQ) or time of flight (TOF) with fully integrated control of the LC for a powerful high throughput analytical or preparative system. Multiple source options include ESI and APCI.

  • expression CMS Single Quadrapole Mass Spectrometer Detector

    The expression CMS range of compact single quadrapole mass spectrometers for small molecule analysis. The CMS can be interfaced with HPLC or SFC for analytical to preparative scale separations. ChromNAV chromatography Data system, includes integrated control for selecting measurement parameters and executing measurement with timed event control for switching polarity and mass range. TIC, EIC and SIM can all be used to monitor chromatograms and to trigger fraction collection for selective fractionation.

Specifications

Specification cms-E cms-S cms-L
Ion Source   ESI, APCI, or APCI/ASAP (direct analysis probe)  
API interface   orthogonal ion sampling from heated capillary – allows for small single turbo pump (Patents pending)  
Flow rate range   10 µL/min to 1 mL/min ESI; 10 µL/min to 2 mL/min APCI  
Polarity   Positive & Negative ion switching in single analysis  
Polarity Switching Speed   50 ms  
m/z Range 80 to 800 m/z 10 to 1,200 m/z 10 to 2,000 m/z
Acquisition speed   10,000 m/z units sec-1 (compatible with UHPLC)  
Resolution   0.5-0.7 m/z units (FWHM) at 1000 m/z units sec-1 over entire acquisition range  
SIM sensitivity   10 pg Reserpine (FIA – 5µL sample injection volume at 100 µL/min) 100:1 S/N (RMS) with SIM of m/z 609.28  
Accuracy   ± 0.1 m/z units over entire acquisition range  
Dynamic Range   4.5 orders of magnitude